Zaditenum - the description, contraindications, application

The latin name: Zaditen

Zaditen Pharmacological groups: Stabilizers of membranes of mast cells

Zaditen Working substance: (Ketotifen *)

Zaditen Application: Prophylaxis of attacks of a bronchial asthma (all forms), an allergic bronchitis, a pollinosis; prophylaxis and treatment of an allergic rhinitis, an allergic conjunctivitis, a urticaria (acute, chronic), a dermatitis, a migraine.

Zaditen Contraindications: Hypersensitivity, pregnancy, a feeding a breast, children's age till 3 years (tablet) or 6 (syrup).

Zaditen Application at pregnancy and a feeding a breast: It counterindicative. For the period of treatment it is necessary to stop thoracal feeding.

Zaditen Side effects: On the part of nervous system and sense organs: a sedation, dropping of reactionary ability, block, sensation of weariness, a mild giddiness, a headache, a sleepiness, it is rare - anxiety, infringement of dream, a nervousness (it is especial at children) . the parties of bodies ZHKT: dryness in a mouth, rising of appetite, a nausea, a vomiting, a gastralgia, a constipation. Other: a thrombocytopenia, a cystitis, augmentation of mass of a body, allergic dermal reactions.

Zaditen Interaction: Strengthens effects of sedative, somnolent, other antihistaminics and ethanol. Peroral antidiabetic preparations enlarge probability of development of a thrombocytopenia.

Zaditen Overdosage: Signs: a sleepiness, a nystagmus, a confusion of consciousness, a desorientation, -or a tachycardia, a hypotension, a short wind, ; cramps, a hyperexcitability (it is especial at children); development of a coma is possible. Treatment: an induction of a vomiting, a gastric lavage, purpose of the activated coal, saline purgative; symptomatic therapy: maintenance of the vital functions, at exaltation and cramps - introduction shortly working or . The dialysis is noneffective.

Zaditen Way of application and dose: Inside, during meal, to adults and children than 3 years the first 3-4 days - on 1 mg in the evening (the sedation is possible), then 2 mg / (on 1 mg in the morning and in the evening) are more senior. If necessary at adults and children than 10 years a daily dose are more senior raise up to 4 mg (on 2 mg 2 times day). A syrup: to children in the age of from 6 till 3 years - in a single dose of 2,5 ml - (0,05 mg / kg) 2 times day; to children than 3 years - on 5 ml (1 . are more senior.) in the first 3-4 days of 1 times in the evening, then 2 times (in the morning and in the evening).

Zaditen Safety measures: it is not intended for a cupping of an attack of a bronchial asthma. It is not recommended to cancel at once previous therapy -, glucocorticoids, (a cancellation carry out during a minimum 2 , gradually reducing doses). With care to apply in an operating time to drivers of vehicles and people which trade is connected to the raised concentration of attention. At the expressed sedative action, in first two weeks appoint on 0,5 mg 2 times day. Treatment stop gradually, during 2-4 (relapse of asthmatic signs is possible). At the patients simultaneously receiving peroral agents, it is necessary to supervise number of thrombocytes in a peripheric blood. It is necessary to take into account, that the syrup contains alcohol (2,35 volumetric %) and carbohydrates (0,6 /ml).

Trading names of preparations with working substance (Ketotifen *):
(Airyfene) (Zetifen) Ketotifenum (Ketotifen Stada) (Asthafen) Ketotifenum (Ketotifen) Ketotifenum of a tablet 0,001 (Tabulettae Ketotifeni 0,001 g) Zaditenum (Zaditen) Ketotifenum 0,001 (Ketotifen 0,001 g) Ketotifenum (Ketotifeni fumaras)