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TOPAMAC (Topamax, Generic Topiramate)


Topamac is manufactured by Janssen Cilag, India.Topiramate is used alone or with other medications to prevent and control seizures (epilepsy). This medication is also used to prevent migraine headaches and reduce how often you may get them. Topiramate will not work to treat a migraine headache once it occurs. If you get a migraine headache, treat it as directed by your doctor (e.g., take pain medications, decrease sound and light).Topiramate is an anti-seizure medication (anticonvulsant) that works in several ways to prevent seizures and migraines.
TOPAMATE ( Topamax, Generic Topiramate )


Topamate is manufactured by Cipla Pharmaceuticals Limited, India.Topiramate is used alone or with other medications to prevent and control seizures (epilepsy). This medication is also used to prevent migraine headaches and reduce how often you may get them. Topiramate will not work to treat a migraine headache once it occurs. If you get a migraine headache, treat it as directed by your doctor (e.g., take pain medications, decrease sound and light).Topiramate is an anti-seizure medication (anticonvulsant) that works in several ways to prevent seizures and migraines.
Topiramate (Generic Topamac, Topamax) Product Origin: United Kingdom


Topiramate is manufactured by Sandoz, United Kingdom.Topiramate is used alone or with other medications to treat certain types of seizures in people who have epilepsy. Topiramate is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topiramate is used to treat patients who continue to have seizures even when they take other anti-seizure medications. Topiramate is also used to prevent migraine headaches, but not to relieve the pain of migraine headaches when they occur. Topiramate is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.
TOPAMAC ( Topamax, Generic Topiramate )


Topiramate is used alone or with other medications to treat certain types of seizures in people who have epilepsy. Topiramate is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topiramate is used to treat patients who continue to have seizures even when they take other anti-seizure medications. Topiramate is also used to prevent migraine headaches, but not to relieve the pain of migraine headaches when they occur. Topiramate is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.
Used with other drugs to control various types of convulsions and seizures of epilepsy.
Topamac/Topamax ( Generic Topiramate )


Topiramate is used for: Treating certain kinds of seizures in patients 2 years of age or older. It is also prescribed to prevent migraine headache in adults. Topiramate is a seizure medication, also called an anticonvulsant.Topiramate is used alone or in combination with other medications to prevent seizures in adults and children who are at least 2 years old. Topiramate is also used to prevent migraine headaches. Topiramate will only prevent migraine headaches or reduce the number of attacks. It will not treat a headache that has already begun.
Common uses -This medicine is an anticonvulsant used alone or with other medicines to control certain types of seizures. It may be also used to prevent migraine headaches or to treat other conditions as determined by your doctor.

Before using -Some medicines or medical conditions may interact with this medicine. INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. ADDITIONAL MONITORING OF YOUR DOSE OR CONDITION may be needed if you are taking birth control pills; carbamazepine; or other medicines that cause decreased sweating including anticholinergic medicines such as benztropine, amitriptyline, and haloperidol, or carbonic anhydrase inhibitors including acetazolamide and dichlorphenamide. DO NOT START OR STOP ANY MEDICINE without doctor or pharmacist approval. Inform your doctor of any other medical conditions, allergies, pregnancy, or breast-feeding. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.

Directions -Follow the directions for using this medicine provided by your doctor. SWALLOW WHOLE. Do not break, crush, or chew before swallowing. This medicine may be taken on an empty stomach or with food. DRINKING EXTRA FLUIDS while you are taking this medicine is recommended. Check with your doctor or nurse for instructions. STORE THIS MEDICINE at room temperature in a tightly-closed container, away from heat and light. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Cautions -DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. DO NOT STOP USING THIS MEDICINE without first checking with your doctor. Some conditions may become worse when the medicine is suddenly stopped. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. Laboratory and/or medical tests may be done, such as measuring bicarbonate levels in your blood, before you start taking this medicine and during therapy to monitor for side effects. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are taking this medicine. THIS MEDICINE WILL ADD TO THE EFFECTS OF ALCOHOL and other depressants. Ask your doctor or pharmacist if you have questions. DO NOT DRIVE, OPERATE MACHINERY, OR DO ANYTHING ELSE THAT COULD BE DANGEROUS until you know how you react to this medicine. Using this medicine alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks. THIS MEDICINE MAY REDUCE SWEATING which could raise your body temperature, especially in children. The risk of this serious side effect is greater in hot weather and/or during vigorous exercise. Drink plenty of fluids and dress lightly while in hot climates, or when exercising. Check carefully for signs of decreased sweating. If this occurs, promptly seek cooler or air-conditioned shelter and/or stop exercising. SEEK IMMEDIATE MEDICAL ATTENTION if your body temperature is above normal, or if you have mental or mood changes, headache, or dizziness. Contact your doctor for more details. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. FOR WOMEN, TAKING THIS MEDICINE while you are using birth control pills may decrease the effectiveness of your birth control pills. To prevent pregnancy, use an additional form of birth control while you are taking this medicine. Ask your doctor or pharmacist if you need more information. IF YOU PLAN ON BECOMING PREGNANT, discuss with your doctor the benefits and risks of using this medicine during pregnancy. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. IF YOU ARE OR WILL BE BREAST-FEEDING while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.

Drug interactions -Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Use our drug interaction checker to find out if your medicines interact with each other. Check drug interactions

If you take too much -If overdose is suspected, contact your local poison control center or emergency room immediately.

Additional information -Laboratory and or medical tests (e.g., eye exams) may be performed to monitor your progress. DO NOT SHARE THIS MEDICINE with others for whom it was not prescribed. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS MEDICINE out of the reach of children. IF USING THIS MEDICINE FOR AN EXTENDED PERIOD OF TIME, obtain refills before your supply runs out.

Generic Topamax (Topiramate)


Topamax (Topiramate) is an anticonvulsant used with other medicines to control certain types of seizures.
Topiramate, Topamax


Used for the treatment and control of partial seizures and severe tonic-clonic (grand mal) seizures and also for the prevention of migraine headaches. In children it is also used for treatment of Lennox-Gastaut syndrome.


Topamax - the description, contraindications, application

The latin name: Topamax



Topamax Pharmacological groups: Antiepileptic agents

Topamax Working substance: Topiramate

Topamax Application: Partial or generalized -clonic attacks as monotherapy and in a combination with other anticonvulsants; padding therapy at treatment of the attacks connected to set of symptoms - (at adults and children); for the first time the diagnosed epilepsy (at adults and children than 2 years are more senior).

Topamax Contraindications: Hypersensitivity.

Topamax Restrictions to application: Pregnancy, a feeding a breast, children's age (safety and efficiency of application for children till 2 years are not determined).

Topamax Application at pregnancy and a feeding a breast: it is Possible, if the expected effect of therapy exceeds potential risk for a fetus (adequate and controllable researches on application during pregnancy it was not carried out). For the period of treatment it is necessary to stop thoracal feeding.

Topamax Side effects: From the side of nervous system and sense organs: undue fatiguability, an ataxia, infringement of thinking and concentration of attention, an emotional lability, a confusion of consciousness, a giddiness, a paresthesia, a hypesthesia, a sleepiness; rarely - exaltation, an amnesia, an aphasia, depression, a diplopia and other infringements of vision, a conjunctivitis, a nystagmus, infringement of speech, a distortion of gustatory sensations. From the side of bodies of the GASTROINTESTINAL TRACT: an anorexia, a ulitis, a nausea. Other: decrease of mass of a body, an abdominal pain, a fever, a leukopenia, a dyspnea, an edema, a nasal bleeding, a nephrolithiasis, a hematuria, , , a dysmenorrhea, weakening of a libido, an impotency.

Topamax Interaction: Phenytoinum and Karbamazepinum depress the maintenance in a blood. reduces AUC digoxin (by 12 %), a level of Phenytoinum in plasma and efficiency of peroral contraceptives. Simultaneous application with the drugs contributing to a nephrolithiasis, can enlarge risk of formation of stones in kidneys.

Topamax Overdosage: Signs: intensifying of side effects. Treatment: a gastric lavage or an induction of a vomiting, a maintenance therapy. In serious cases probably carrying out of a haemodialysis.

Topamax Way of application and dose: Inside (irrespective of reception of nutrition). The adult at monotherapy: an initial dose - 25 mg of 1 times day (for the night) during 1 weeks, then a dose enlarge on 25-50 a milligram/day (divide into 2 receptions) with an interval 1-2 weeks up to achievement of clinical effect; an advisable dose - 100 milligram/day, maximal diurnal - 500 mg (for some patients with refractory forms of an epilepsy - up to 1000 milligram/day). To children than 2 years are more senior: in the first week of treatment - 0,5-1 mg / kg for the night, then a dose enlarge by 0,5-1 mg (divide into 2 receptions) with an interval 1-2 weeks; advisable doses - 3-6 mg (for children with recently diagnosed partial attacks - up to 500 milligram/day). In a combination to other antispasmodic drugs: adult - 25-50 mg for the night during 1 weeks, then a dose enlarge by 25-50 mg with an interval 1-2 weeks and accept in 2 receptions; a minimum efficient dose - 200 milligram/day, center diurnal - 200-400 mg, maximal - 1600 mg. To children than 2 years are more senior: - 1-3 mg for the night during 1 weeks, then a dose enlarge by 1-3 mg / kg with an interval 1-2 weeks and accept in 2 receptions; an advisable daily dose - 5-9 mg / kg.

Topamax Precautionary measures: the Patients who are taking place on a haemodialysis, in days of his carrying out it is necessary to yield a padding dose (approximately 1/2 day time doses) before procedure. A cancellation carry out gradually, reducing a dose on 100 mg with week intervals. At patients with the raised risk of a nephrolithiasis adequate rising volume of a consumed liquid is recommended. With care apply at patients with infringement of function of a liver (because of possible downstroke of a clearance ). Cases of occurrence of the secondary angle-closure glaucoma at children and adults are possible. In case of appreciable loss of mass of a body at treatment the suralimentation or application of alimentary additives is necessary. It is not necessary to apply in an operating time to drivers of vehicles and people which trade is connected to the raised concentration of attention. It is not recommended to accept simultaneously with alcohol or the drugs oppressing with the CNS.

Trading names of drugs with working substance Topiramate:
(Topamax)

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