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Synthivan (Reyataz, Norvir, Generic Atazanavir/Ritonavir)


Synthivan is manufactured by Cipla Pharmaceuticals Limited, india.SYNTHIVAN is indicated in combination with other antiretroviral agents in HIV-infected adults and children (weighing at least 39 kg and between 6-18 years of age) The following points should be considered when initiating therapy with atazanavir/ritonavir: In Study AI424-045 atazanavir /ritonavir and lopinavir/ritonavir were similar for the primary efficacy outcome measure of time-averaged difference in change from baseline in HIV RNA level. This study was not large enough to reach a definitive conclusion that atazanavir/ritonavir and lopinavir/ritonavir are equivalent on the secondary efficacy outcome measure of proportions below the HIV RNA lower limit of detection. The number of baseline primary protease inhibitor mutations affects the virologic response to atazanavir/ritonavir. DOSAGE AND ADMINISTRATION General Dosing Recommendations: SYNTHIVAN must be taken with food. The recommended oral dosage of SYNTHIVAN depends on the treatment history of the patient and the use of other co-administered drugs. When co-administered with H2-receptor antagonists or proton-pump inhibitors, dose separation may be required. When co-administered with didanosine buffered or enteric-coated formulations, SYNTHIVAN Tablets should be given with food 2 hours before or 1 hour after didanosine. Efficacy and safety of atazanavir with ritonavir in doses greater than 100 mg once daily have not been established. The use of higher ritonavir doses might alter the safety profile of atazanavir (cardiac effects, hyperbilirubinemia) and, therefore, is not recommended. Recommended Adult Dosage Dose Recommendations for Therapy-Naive Patients For treatment-naive patients, the recommended dosage is 1 SYNTHIVAN tablet with food.
Ritomune ( Norvir, Generic Ritonavir )


Ritomune is manufactured by Cipla Pharmaceuticals Limited, India.This drug, used in combination with at least 2 other medications, helps to control your HIV infection, thereby improving your quality of life. It also lowers your risk of getting HIV complications (e.g., new infections, cancer). Ritonavir belongs to a class of drugs known as protease inhibitors.Ritonavir is not a cure for HIV and it does not prevent the spread of HIV to others through sexual contact or blood contamination (e.g., sharing used needles).



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