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Ezetimibe (e-ZET-e-mibe) is used to lower cholesterol and triglyceride (fat-like substances) levels in the blood. Using this medicine may help prevent medical problems caused by such substances clogging the blood vessels.
Ezetimibe is a new kind of cholesterol-lowering drug. The older cholesterol-lowering drugs called "statins" reduce cholesterol by interfering with its production in the body. Zetia acts by diminishing the absorption of dietary cholesterol through the intestines.
Ezetimibe may be taken alone or with a statin drug. Because the two drugs fight cholesterol in different ways, the Ezetimibe/statin combination has a greater impact than either drug alone.
Cholesterol--especially "bad" LDL cholesterol--promotes clogged arteries, increasing the risk of heart attack and stroke. "Good" HDL cholesterol helps to prevent clogged arteries. Zetia lowers the bad cholesterol and raises the good. It also lowers total cholesterol readings and reduces levels of triglycerides (fats in the blood).
Cholesterol-lowering drugs are typically prescribed for people who either have heart disease or are in danger of developing it. For people at high risk of heart disease, current guidelines call for considering drug therapy when LDL levels reach 130. For people at lower risk, the cut-off is 160. For those at little or no risk, it's 190.Inhibits absorption of cholesterol by the small intestine.Ezetimibe reduces the amount of cholesterol absorbed by the body.
Ezetimibe is used to treat high cholesterol. Ezetimibe is sometimes given with other cholesterol-lowering medications.
Ezetrol is used either alone or with other cholesterol lowering drugs (e.g., HMG-CoA reductase inhibitors or "statins"), along with a cholesterol-lowering diet, to help lower cholesterol in the blood. Reducing cholesterol helps prevent strokes and heart attacks. Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet.
Before Use - Some medicines or medical conditions may interact with this medicine. Inform you Doctor or Pharmacist of all prescription and over-the-counter medicine that you are taking.
Additonal monitoring of your dose or condition may be needed if you are taking fibrates (e.g., gemfibrozil, fenofibrate), or cyclosporine. Inform your doctor of any other medical conditions including moderate to severe liver disease, allergies, pregnancy, or breast-feeding.
Use of Ezetrol is not recommended if you have active liver disease. Contact your doctor or pharmacist if you have any questions or concerns about taking this medicine.
Directions -Follow the directions for using this medicine provided by your doctor. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine.
Ezetrol may be taken on an empty stomach or with food.
If you are also taking a bile acid sequestrant (e.g., cholestyramine, colestipol, or colesevelam), take ezetimibe at least 2 hours before or at least 4 hours after the bile acid sequestrant.
Store Ezetrol at room temperature at 77°F (25°C), away from heat and light. Brief storage between 59°F and 86°F (15°F and 30°C) is permitted.
Do not store Ezetrol in the bathroom.
Continue taking Ezetrol even if you feel well. Most people with high cholesterol do not feel sick.
Do not miss any doses. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Cautions -Do not take Ezetrol if you have had an allergic reaction to it or are allergic to any ingredient in this product.
It may take 2 weeks for this medicine to work. Do not stop taking this medicine without checking with your doctor.
Laboratory and/or medical tests, including cholesterol levels, liver function tests, blood counts, and creatine phosphokinase (CPK) levels, may be performed while you are taking this medicine to monitor your progress or to check for side effects. Keep all doctor and laboratory appointments while you are using this medicine.
When ezetimibe is given with a statin agent, liver function tests should be performed to monitor for side effects. Consult your doctor for more details.
Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist.
For Women -If you become pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy.
It is unknown id this medicine is excreted in breast milk. If you are or will be breast-feeding while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.
Side Effects -Side effects that may occur while taking Ezetrol include
dizziness headache diarrhea nausea stuffy nose
If they continue or are bothersome, check with your doctor.
Check with your doctor as soon as possible if you experience
fever, chills, or sore throat joint or muscle pain or tenderness unusual bruising or bleeding stomach pain
Contact you Doctor immediately if you experience -
chest pain yellowing of the eyes or skin swelling of hands, face, lips, eyes, throat, or tongue difficulty swallowing or breathing hoarseness
An allergic reaction to this medicine in unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include -
rash itching swelling dizziness trouble breathing
If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.