Clomid - the description, contraindications, application

The latin name: Clomid

Clomid Pharmacological groups: Estrogens, gestagens; their homologues and antagonists

Clomid Working substance: Clomifene

Clomid Application: Anovulatory barreness (an induction of an ovulation), dysfunctional uterine bleedings, an amenorrhea (secondary, postcontraceptive), a galactorrhea (on a background of a tumour of a pituitary body), a polycystosis of ovaries , androgenic failure, an oligospermatism, for diagnostics of infringements of gonadotrophic function of a pituitary body.

Clomid Contraindications: Hypersensitivity, serious hepatonephric failure, uterine bleedings of an obscure etiology, an oothecoma, a tumour or failure of function of a pituitary body, pregnancy (including suspicion on it).

Clomid Application at pregnancy and a feeding a breast: It counterindicative at pregnancy.

Clomid Side effects: On the part of nervous system and sense organs: a headache, a giddiness, depression, undue fatiguability, anxiety, a sleeplessness, infringement of vision. On the part of bodies of the GASTROINTESTINAL TRACT: a nausea, a vomiting. On the part of genitourinary system: cystic augmentation of ovaries, a dysmenorrhea, a pollakiuria, a polyuria, multiple pregnancy. Other: inflow, augmentation of mass of a body, a pain in the bottom of a stomach, in the field of a breast, testicles (at men), a hyperthermia, convertible abaissement of hair, allergic dermal reactions.

Clomid Interaction: we Compose to preparations of gonadotrophic Hormonums.

Clomid Overdosage: Signs: a nausea, a vomiting, inflow, visual disturbances, an abdominal pain. Treatment: symptomatic therapy.

Clomid Way of application and dose: Inside. For a stimulation of an ovulation appoint on 50 mg of 1 times day before dream, since 5-th day of a menstrual cycle within 5 days (at absence of a cycle - at any time); if the effect is not present (an ovulation does not occur within 30 days), enlarge a dose up to 100 milligram/day or extend a course till 10 days. The course dose should not exceed 750 mg. Offensive of an ovulation is defined on presence of biphase basal temperature, average cyclic rising of production of the LUTEINIZING HORMONE, body height of a level of serumal Progesteronum during a probable average phase of a luteinization or at a menstrual bleeding of women with an amenorrhea. If the ovulation has taken place, and pregnancy has not come, the course should be repeated. If after a holding ovulation has not followed a menstrual bleeding, it is necessary to take into account possible pregnancy. To men appoint on 50 mg 1-2 times day during 3-4 month (the regular control spermatogrammas is necessary).

Clomid Safety measures: Prior to the beginning and during treatment constant observation of the gynecologist is necessary, it is necessary to check function of ovaries, to carry out vaginal examonations, to observe of a phenomenon of "pupil", etc. At augmentation of ovaries or their cystic transformation treatment by a clomiphene stop before normalization of the sizes of ovaries. Therapy continue with use of the minimal doses or shorten the period of treatment. On a background of treatment it is recommended to supervise function of a liver. It is impossible to appoint without remission of work to persons which professional work demands fast physical and mental reactions.

Trading names of preparations with working substance Clomifene:
(Clomid) (Clostilbegyt)