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Drugs groupShort description
Nifelat ( Adalat, Procardia, Calcigard, Generic Nifedipine )


Nifelat is manufactured by Cipla Pharma, India.This medication is used to prevent certain types of chest pain (angina). It may allow you to exercise more and decrease the frequency of angina attacks. Nifedipine belongs to a class of medications known as calcium channel blockers. It works by relaxing blood vessels so blood can flow more easily. This medication must be taken regularly to be effective. It should not be used to treat attacks of chest pain when they occur. Use other medications (such as sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor. Consult your doctor or pharmacist for details.
Calcigard ( Adalat, Procardia, Generic Nifedipine )


This medication is used for certain types of chest pain (angina). It may help to increase exercise tolerance and decrease the frequency of angina attacks. Nifedipine belongs to a class of medications known as calcium channel blockers. It works by relaxing blood vessels so blood can flow more easily. This medication must be taken regularly to be effective. It should not be used to treat attacks of chest pain when they occur. Use other medications (e.g., sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor. Consult your doctor or pharmacist for details.OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This medication may also be used alone or in combination with other drugs to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.This medication may also be used to treat certain blood circulation disorders (Raynaud's syndrome).How to use Nifedipine OralTake this medication by mouth on an empty stomach, usually three times daily or as directed by your doctor. Swallow this medication whole. Do not crush, chew, or break the capsules.Your doctor may gradually increase your dose. Follow your doctor's instructions carefully. The dosage is based on your age, medical condition and response to therapy.Avoid eating grapefruit or drinking grapefruit juice while taking this medication unless your doctor instructs you otherwise. Grapefruit juice can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details.Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.Do not suddenly stop taking this medication without consulting your doctor. Your condition may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.Inform your doctor if your condition worsens (e.g., your routine blood pressure readings increase).
Used to treat high blood pressure. If taken regularly, nifedipine controls chest pain, but it does not stop chest pain once it starts. Your doctor may give you a different medication to take when you have chest pain.


Calcigard Retard - the description, contraindications, application

The latin name: Calcigard Retard



Calcigard Pharmacological groups: Blockers of calcium canals

Calcigard Working substance: Nifedipinum (Nifedipine)

Calcigard Application: the Arterial hypertension, including a hypertonic crisis, prophylaxis of attacks of a stenocardia (including stenocardias ), a hypertrophic cardiomyopathy (obstructive, etc.), a Raynaud's disease, a pulmonary hypertension, a set of symptoms.

Calcigard Contraindications: Hypersensitivity, the acute period of a myocardial infarction (the first 8 days), a cardiogenic shock, a serious aortal stenosis, a heart failure in a stage of the decompensation, the expressed arterial hypotension, a tachycardia, pregnancy, a feeding a breast.

Calcigard Restrictions to application: It is necessary to refrain from application of a drug in pediatric practice as safety and efficiency of his application for children are not determined.

Calcigard Application at pregnancy and a feeding a breast: It counterindicative. For the period of treatment it is necessary to stop thoracal feeding.

Calcigard Side effects: From the side of cardiovascular system and a blood (a hemopoiesis, a hemostasis: frequently (in the beginning of treatment) - a hyperemia of the person with sensation of fever, palpitation, a tachycardia; rarely - a hypotension (down to a syncope), a pain similar stenopeic, it is very rare - an anemia, a leukopenia, a thrombocytopenia, a Werlhof's disease. From the side of nervous system and sense organs: in the beginning of treatment - the giddiness, a headache, is rare - an obnubilation, very rare - change of a vision, infringement of sensitivity in arms and legs. From the side of bodies of the GASTROINTESTINAL TRACT: frequently - a constipation, it is rare - a nausea, a diarrhea, it is very rare - a hyperplasia a gum (at long treatment), rising of activity of hepatic transaminases. From the side of respiratory system: very rarely - a spastic stricture of bronchuses. From the side of a locomotorium: very rarely - a myalgia, a tremor. Allergic reactions: an itch, a urticaria, exanthemas, it is rare - an exfoliative dermatitis. Other: Frequently (in the beginning of treatment) - a tumescence and a reddening of arms and legs, it is very rare - a photodermatitis, a hyperglycemia, a gynecomastia (at patients of advanced age), sensation of a burning sensation in a place of an injection (at intravenously introduction).

Calcigard Interaction: Sodium nitritums, beta - adrenoblockers, diuretics, tricyclic antidepressants, Fentanylum, alcohol - strengthen hypotensive effect. Rises activity of Theophyllinum, reduces a renal clearance of digoxin. Strengthens side effects of Vincristinum (reduces deducing). Rises bioavailability of cephalosporins . Cimetidinum and rise a level in plasma. Diltiazems retards a metabolism (decrease of a dose of Nifedipinum is required). It is incompatible with Rifampicinum (accelerates a biotransformation and does not allow to frame efficiency concentrations). Juice of a grapefruit (plenty) enlarges bioavailability.

Calcigard Overdosage: Signs: a sharp bradycardia, a bradyarrhythmia, an arterial hypotension, in serious cases - a collapse, retardation of conduction. At reception of the big number of -tablets attributes of an intoxication are displaid not earlier than in 3-4 h and hyperglycemias, a metabolic acidosis, a hypoxia can follow-up be expressed in a loss of consciousness down to a coma, a cardiogenic shock, cramps. Treatment: a gastric lavage, reception of absorbent coal, introduction of Norepinephrinum, calcium of Sodium chloridum or calcium of a gluconate in a solution of Atropinum (intravenously). The haemodialysis is noneffective.

Calcigard Way of application and dose: Inside, sublingually, intravenously. Inside, during time or after meal, as tablets, sheaths, a dragee, the adult - on 10 mg 3-4 times day. In special cases (an alternative stenocardia, a serious arterial hypertension) - the augmentation of a dose up to 20 mg of 4-6 times day for short time is possible. A maximal daily dose - 120 mg. At an arterial hypertension - on 10 mg 3 times day (if necessary a dose enlarge within 7-14 days up to 20-30 mg by reception. For a cupping of a hypertonic crisis and an attack of a stenocardia of 10-20 mg sublingually or inside it is single-pass, if necessary - through 10 mines repeatedly as sheaths and tablets of prolonged action (the sheath is recommended to be got to the core or pierced preliminarily) - on 20-40 mg 2 times day (at stenocardia - up to 120 milligram/day); as tablets - 40-80 mg of 1 times day (the tab. do not chew). Intravenously (a cupping of a hypertonic crisis) - 5 mg within 4-8 h (0,0104-0,0208 mg / mines), or 6,3-12,5 mls / h). A maximal dose - 15-30 milligram/day (can be utilised no more than 3 days).

Calcigard Precautionary measures: Elderly patients are recommended to decrease a daily dose (dropping of a metabolism). With care to apply in an operating time to drivers of vehicles and people which trade is connected to the raised concentration of attention. To cancel a drug follows gradually (probably development of a withdrawal).

Calcigard Special indicatings: patients with a stable stenocardia in the beginning of treatment can have paradoxical intensifying of anginal pains, at the expressed coronarosclerosis and a unstable stenocardia - aggravation of an ischemia of a myocardium. It is not recommended to use drugs of short action for long treatment of a stenocardia or an arterial hypertension since development of unpredictable changes the HELL and a reflex stenocardia is possible.

Trading names of drugs with working substance Nifedipine:
Adalatum (Adalat) (Cordipin XL) Nifedipinum - (Nifedipin-Farkos) Adalatum (Adalat SL) (Cordipin retard) Nifedipinum - (Nifedipin-FPO) -Nifedipinum (Vero-Nifedipine) Corinfarum (Corinfar) (Nifecard XL) -? (Depin-E) Corinfarum (Corinfar retard) Nifelatum (Nifelat) (Calcigard Retard) (Nicardia) Adalatum (Osmo-Adalat) - (Carin-Fer) (Nicardia CD retard) (Fenamon) (Cordafen) Nifedipinum (Nifedipin) Phenihydinum (Phenyhydinum) (Cordaflex) Nifedipinum - (Nifedipin-MIK) Phenihydinum of a tablet of 0,01 g (Tabulettae Phenihidini 0,01 g) (Cordipin) Nifedipinum - (Nifedipin-ratiopharm)

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