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Medical Information:

AVANDIA (rosiglitazone maleate) is an oral antidiabetic agent which acts primarily by increasing insulin sensitivity.

AVANDIA improves glycemic control while reducing circulating insulin levels.

AVANDIA is indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Due to its mechanism of action, AVANDIA is active only in the presence of endogenous insulin. Therefore, AVANDIA should not be used in patients with type 1 diabetes mellitus or for the treatment of diabetic ketoacidosis.

The coadministration of AVANDIA and insulin is not recommended. The use of AVANDIA with nitrates is not recommended.
Rosiglitazone (Avandia) is used, alone or in combination with other medications, to treat type 2 (noninsulin-dependent) diabetes (formerly "adult-onset") in people whose diabetes cannot be controlled by diet and exercise alone. Rosiglitazone (Avandia) is in a class of drugs called thiazolidinediones. These drugs work by increasing your bodys sensitivity to insulin, a substance your body produces to help control blood sugar levels. Rosiglitazone (Avandia) is not used to treat type 1 (insulin-dependent) diabetes (formerly "juvenile-onset").

Avandia is sometimes prescribed for other uses; ask your doctor or pharmacist for more Avandia information.

How should Avandia be used?Rosiglitazone (Avandia) comes as a tablet to take by mouth. Avandia is usually taken once or twice daily with or without meals. Follow the Avandia directions on your Avandia prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take rosiglitazone (Avandia) exactly as directed. Do not take more or less of Avandia or take Avandia more often than prescribed by your doctor.

Rosiglitazone (Avandia) controls type 2 diabetes but does not cure it. Continue to take rosiglitazone (Avandia) even if you feel well. Do not stop taking rosiglitazone (Avandia) without talking to your doctor.